細(xì)胞組織微電極陣列拉伸刺激與成像記錄系統(tǒng)，細(xì)胞組織拉伸電刺激測量分析系統(tǒng)，細(xì)胞電極應(yīng)力刺激系統(tǒng)，微電極及機(jī)械力刺激系統(tǒng)，微電極耦合機(jī)械力刺激系統(tǒng)，微電極同時(shí)機(jī)械力刺激系統(tǒng)，微電極偶聯(lián)機(jī)械力刺激系統(tǒng)

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細(xì)胞組織微電極陣列拉伸刺激與成像記錄系統(tǒng)

該細(xì)胞組織微電極陣列拉伸刺激與成像記錄系統(tǒng)使研究人員能夠可重復(fù)且可靠地研究生理和病理機(jī)械拉伸對(duì)生物組織電生理的影響。該系統(tǒng)集成：（1）細(xì)胞拉伸設(shè)備；（2）電生理數(shù)據(jù)采集系統(tǒng)；（3）活細(xì)胞成像系統(tǒng)三種功能。每個(gè)模塊都可以作為立工具使用

該細(xì)胞組織微電極陣列拉伸刺激與成像記錄系統(tǒng)是研究人員以機(jī)械方式拉伸細(xì)胞/組織，對(duì)其進(jìn)行光學(xué)成像以及單/同時(shí)記錄/刺激電生理活動(dòng)的完整解決方案。

細(xì)胞、組織拉伸功能：

★雙軸，單軸
★自定義應(yīng)變場
★一種快速?zèng)_動(dòng)拉伸或周期性拉伸
★高達(dá)50％的應(yīng)變
★應(yīng)變速率高達(dá)80 / s
★任何拉伸圖案
★高重復(fù)性

成像功能：
★拉伸之前，期間和之后
★2MP分辨率下每秒高達(dá)2,000幀
★定制，易于使用的軟件可立測量組織應(yīng)變

電生理學(xué)功能：
★電極同時(shí)細(xì)胞/組織伸展
★伸展前，伸展中和伸展后記錄/刺激
★拉伸前后電生理活動(dòng)的比較（標(biāo)準(zhǔn)化）
★彈性硅樹脂基材上的軟MEA
★可以在硬質(zhì)基材上使用標(biāo)準(zhǔn)MEA

應(yīng)用文獻(xiàn)（Publications）：

O Graudejus, T. Li, J. Cheng, N. Keiper, R.D. Ponce Wong, A.B. Pak, J. Abbas, The effects of bending on the resistance of elastically stretchable metal conductors, and a comparison with stretching. Applied Physics Letters, 2017, 110, 221906

W. H. Kang, W. Cao, O. Graudejus, T. Patel, S. Wagner, D. Meaney, B. Morrison III, Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury, Journal of Neurotrauma, 2015, 32(13), 1011-1019

O. Graudejus, Z. Jia, T. Li, S. Wagner, Size dependent rupture strain of elastically stretchable metal conductors, Scripta Materialia, 2012, 66, 919-922

O. Graudejus, B. Morrison, C. Goletiani, Z. Yu, S. Wagner, Encapsulating elastically stretchable neural interfaces: yield, resolution, and recording/stimulation of neural activity, Advanced Functional Materials, 2012, 22, 640-651 

J. Jones, O. Graudejus, S. Wagner, Elastically stretchable insulation and bi-level metallization and its application in a stretchable RLC circuit, Journal of Electronic Materials, 2011, 40(6), 1335-1344. 

O. Graudejus, P. G●rrn, S. Wagner, Controlling the morphology of gold films on poly(dimethylsiloxane), ACS Applied Materials & Interfaces, 2010, 2(7), 1927-1933 

S. P. Lacour, S. Benmerah, E. Tarte, J. FitzGerald, J. Serra, S. McMahon, J. Fawcett, O. Graudejus, Z. Yu, B Morrison, Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces, Medical & Biological Engineering Computation, 2010, 48(10), 945-954 (Special Issue) 

Z. Yu, O. Graudejus, C. Tsay, S. P. Lacour, S. Wagner, B. Morrison, Monitoring hippocampus electrical activity in vitro on an elastically deformable microelectrode array, Journal of Neurotrauma, 2009, 26(7), 1135-1145 

O. Graudejus, Z. Yu, J. Jones, B. Morrison III, S. Wagner, Characterization of an elastically stretchable microelectrode array and its application to neural field potential recordings, Journal of the Electrochemical Society, 2009, 156(6) P85-P94 

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